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Part III: Guidelines for selected antimicrobial use
- Ceftaroline is a newer cephalosporin with in vitro activity against MRSA.
- Ceftaroline is inactive against ESBL-producing or AmpC-overexpressing Enterobacteriaceae and has limited activity against non-fermenting Gram-negative bacilli such as Pseudomonas aeruginosa and Acinetobacter baumannii (168).
- Community acquired pneumonia: 600 mg I.V. q12h
- Skin and soft tissue infection: 600 mg I.V. q12h
- Consult clinical microbiologist or infectious disease physician for the use of ceftaroline.