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Hong Kong West Cluster

Table HKW-2. Antibiogram for blood isolates, HKW, 2018

Table HKW-2. Antibiogram for blood culture isolates, HKW, 2018

  1. Non-duplicate isolates from blood, urine and respiratory specimens. Interpreted according to CLSI M100-S28 2018. Nonsusceptible include both intermediate & resistant.
  2. Results for Enterobacteriaceae were interpreted according to CLSI M100-S28 2018. A total of 45 sporadic carbspenemase - producing Enterobacteriaceae (CPE) were detected in blood (n=5), respiratory (n=11) and urine (n-29) specimens from 33 patients in diverse locations. The eniyme types included NDM (n=28), OXA-48(n-16) and KPC (n=1)
  3. HoPL Int J Antimicrob Agents 2010;36:469 and J Hosp Infect 2010;74:358
  4. Overall prevalance of extended-spectrum beta-lactamases (ESBL) were 26% for Klebsiella species, 29% for E. coli. ESBL-producing strains should be interpreted as resistant to all penicillins, cephalosporins and aztreonam.
  5. In S. pneumoniae, resistance to azithromycin and clarithromycin can be predicted by testing erythromycin (CLSI M100-S28 2018).
  6. Most had other risk factor such as past hospitalization and nursing home residence.
  7. HoPL J Antimicrob Chemo 2009;63:836
  8. According to breakpoint for parenteral cefuroxime sodium.
  9. Urine isolates only.
  10. , indicate 10% or more reduction in resistance rate compared to 2017.
    , indicate ≥10% increase in resistance rate compared to 2017.
  11. The figure refers to ACB complex including Acinetobacter baumannii, Acinetobacter calcoaceticus, Acinetobacter nosocomialis and Acinetobacter pitti.

* Including MIC ≤ 0.06 (47.1%), MIC 0.09-1 (24.0%), MIC 1.5-2 (26.9%), MIC 3-6 (1.9%)
%Penicllin sensitive: meningitis breakpoint at MIC ≤0.06 = 47.1% and non-meningitis breakpoint at MIC≤2 = 98.1%
Abbreviation: Amp, Ampicillin; Amo, Amoxicillin; Pip, Pipercillin; Tic, Ticaraillin; Cef, Cefoperazone