Part III: Guidelines for Selected Antimicrobial Use

3.12 Cefepime-taniborbactam

1. Taniborbactam is a boronic-acid-containing β-lactamase inhibitor that inhibits Ambler class A, C, D, and class B β-lactamases, including VIM, NDM, SPM-1, and GIM-1 [254] but not IMP-type metallo-β-lactamases. [271]

2. Cefepime-taniborbactam is an investigational β-lactam and β-lactamase inhibitor combination which has shown activity against Enterobacterales species and Pseudomonas aeruginosa expressing serine- and metallo-β-lactamases. [272]

3. At the time of writing, cefepime-taniborbactam is not available in Hong Kong. Please consult a clinical microbiologist or infectious disease physician regarding the use of cefepime-taniborbactam.