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Table 7.5 Intra-peritoneal antibiotic dosing recommendations for patients with continuous ambulatory peritoneal dialysis peritonitis

Antibiotics Intermittent dosing (once daily)1
(Add drug into 1 bag/day unless otherwise specified) (511)
Aminoglycosides
Amikacin 2 mg/kg
Gentamicin 0.6 mg/kg
Tobramycin 0.6 mg/kg
Cephalosporins
Cefazolin 15 mg/kg
Cefepime 1 g
Ceftazidime 1–1.5 g
Others
Ampicillin-sulbactam 2 g q12h
Imipenem-cilastatin 1 g q12h

 

Note:

  1. 1In patients with residual renal function, the drug dose should be empirically increased by 25%.