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Table 7.5 Intra-peritoneal antibiotic dosing recommendations for patients with continuous ambulatory peritoneal dialysis peritonitis
Antibiotics | Intermittent dosing (once daily)1 (Add drug into 1 bag/day unless otherwise specified) (511) |
---|---|
Aminoglycosides | |
Amikacin | 2 mg/kg |
Gentamicin | 0.6 mg/kg |
Tobramycin | 0.6 mg/kg |
Cephalosporins | |
Cefazolin | 15 mg/kg |
Cefepime | 1 g |
Ceftazidime | 1–1.5 g |
Others | |
Ampicillin-sulbactam | 2 g q12h |
Imipenem-cilastatin | 1 g q12h |
Note:
- 1In patients with residual renal function, the drug dose should be empirically increased by 25%.