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Table 7.3 Cost comparison of systemic antifungal agents
| Antifungal agent | Usual dosage | Cost (HK$/day) |
|---|---|---|
| P.O. itraconazole (capsule) | 200 mg b.d. | 9 |
| P.O. itraconazole (solution) | 200 mg b.d. | 285 |
| I.V. itraconazole | 200 mg q12h | 1,473 |
| P.O. fluconazole (capsule) | 100–400 mg once daily | 3–13 |
| P.O. fluconazole (suspension) | 100–400 mg once daily | 81–323 |
| I.V. fluconazole | 200–400 mg q24h | 82–165 |
| P.O. posaconazole (suspension) | Prophylaxis: 200 mg t.d.s. | 564 |
| P.O. voriconazole | 200 mg b.d. | 889 |
| I.V. voriconazole1 | Loading 6 mg/kg (300 mg) q12h (Day 1) | 1,822–3,644 |
| Maintenance 4 mg/kg (200 mg) q12h | ||
| I.V. anidulafungin | Candidaemia: Loading 200 mg (Day 1) Maintenance 100 mg q24h |
768–1,535 |
| Oesophageal candidiasis: Loading 100 mg (Day 1) Maintenance 50 mg q24h |
768 | |
| I.V. micafungin | Prophylaxis in haematopoietic
stem cell transplantation (HSCT): 50 mg q24h |
321 |
| Candidaemia, acute disseminated candidiasis, Candida peritonitis and abscesses: 100 mg q24h |
642 | |
| Oesophageal candidiasis: 150 mg q24h |
964 | |
| I.V. caspofungin | Invasive aspergillosis: Loading 70 mg (Day 1) Maintenance 50 mg q24h |
2,000 (70 mg) 2,975 (50 mg) |
| I.V. amphotericin B (1 mg/kg/day)1 |
50 mg q24h | 197 |
| I.V. liposomal amphotericin B (3 mg/kg/day)1 |
150 mg q24h | 5,045 |
Note: Approximate cost updated as of June 2016 in HA.
- 1Dosage for a typical 50 kg person.
