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Table 7.3 Cost comparison of systemic antifungal agents

Antifungal agent Usual dosage Cost (HK$/day)
P.O. itraconazole (capsule) 200 mg b.d. 9
P.O. itraconazole (solution) 200 mg b.d. 285
I.V. itraconazole 200 mg q12h 1,473
P.O. fluconazole (capsule) 100–400 mg once daily 3–13
P.O. fluconazole (suspension) 100–400 mg once daily 81–323
I.V. fluconazole 200–400 mg q24h 82–165
P.O. posaconazole (suspension) Prophylaxis: 200 mg t.d.s. 564
P.O. voriconazole 200 mg b.d. 889
I.V. voriconazole1 Loading 6 mg/kg (300 mg) q12h (Day 1) 1,822–3,644
Maintenance 4 mg/kg (200 mg) q12h
I.V. anidulafungin Candidaemia:
Loading 200 mg (Day 1)
Maintenance 100 mg q24h		 768–1,535
Oesophageal candidiasis:
Loading 100 mg (Day 1)
Maintenance 50 mg q24h		 768
I.V. micafungin Prophylaxis in haematopoietic stem cell transplantation (HSCT):
50 mg q24h		 321
Candidaemia, acute disseminated candidiasis, Candida peritonitis and abscesses:
100 mg q24h		 642
Oesophageal candidiasis:
150 mg q24h		 964
I.V. caspofungin Invasive aspergillosis:
Loading 70 mg (Day 1)
Maintenance 50 mg q24h		 2,000 (70 mg)
2,975 (50 mg)
I.V. amphotericin B
(1 mg/kg/day)1
 50 mg q24h 197
I.V. liposomal amphotericin B
(3 mg/kg/day)1		 150 mg q24h 5,045

 

Note: Approximate cost updated as of June 2016 in HA.

  1. 1Dosage for a typical 50 kg person.