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Bedside Index of Severity in Acute Pancreatitis (BISAP) Score

Within the first 24 hours of hospitalisation

BUN > 25mg/dL (8.9 mmol/L)

Yes

Impaired mental status (Glasgow coma score < 15)

Yes

Evidence of SIRS (Severe Inflammatory Response Syndrome)
(any 2 of the 4 criteria below)

Temp >38°C (100.4°F) or < 36°C (96.8°F)
Heart rate > 90/minute
Respiratory rate > 20/minute or PaCO2 < 32 mmHg (4.3 kPa)
WBC > 12,000/uL, < 4,000/uL, or> 10% immature (band) forms

Yes

Age > 60 years

Yes

Pleural effusion

Yes

BISAP score

Mortality rate

Ranson's Criteria

At admission

Age > 55 years

Yes

WBC > 16,000/ul

Yes

Glucose > 11.1 mmol/L (> 200 mg/dL)

Yes

LDH > 350 IU/L

Yes

AST > 250 IU/L

Yes

During initial 48 hours

Haematocrit decrease > 10%

Yes

BUN increase > 1.8 mmol/L (> 5mg/dL)

Yes

Calcium < 2 mmol/L (< 8 mg/dL)

Yes

PaO2 < 60 mmHg

Yes

Base deficit > 4 mEq/L

Yes

Fluid sequestration > 6 L

Yes

Ranson's score

Mortality rate

Formula

BISAP score	Mortality rate
0-1	0.1-0.7%
2	1.9-2.1%
3	5.3-8.3%
4	12.7-19.3%
5	22.5-26.7%

Reference:

Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut. 2008;57(12):1698-1703. doi:10.1136/gut.2008.152702

Ranson's score	Mortality rate
0-2	~1%
3-5	15-20%
6	40%
>6	100% (associated with more systemic complications)

Reference:

Ranson JH, Rifkind KM, Roses DF, Fink SD, Eng K, Spencer FC. Prognostic signs and the role of operative management in acute pancreatitis. Surgery, gynecology & obstetrics. 1974;139(1):69–81.