Calculator

Bedside Index of Severity in Acute Pancreatitis (BISAP) Score

Within the first 24 hours of hospitalisation

BUN >25mg/dL (8.9 mmol/L)

Yes

Impaired mental status (Glasgow coma score <15)

Yes

Evidence of SIRS (Severe Inflammatory Response Syndrome)
(any 2 of the 4 criteria below)

Temp >38°C (100.4°F) or <36°C (96.8°F)
Heart rate >90/minute
Respiratory rate >20/minute or PaCO2 <32 mmHg (4.3 kPa)
WBC >12,000/µL, <4,000/µL, or >10% immature (band) forms

Yes

Age >60 years

Yes

Pleural effusion

Yes

BISAP score

Mortality rate

Ranson's Criteria

At admission

Age >55 years

Yes

WBC >16,000/µL

Yes

Glucose >11.1 mmol/L (>200 mg/dL)

Yes

LDH >350 IU/L

Yes

AST >250 IU/L

Yes

During initial 48 hours

Haematocrit decrease >10%

Yes

BUN increase >1.8 mmol/L (>5mg/dL)

Yes

Calcium <2 mmol/L (<8 mg/dL)

Yes

PaO2 <60 mmHg

Yes

Base deficit >4 mEq/L

Yes

Fluid sequestration >6 L

Yes

Ranson's score

Mortality rate

Formula

BISAP score	Mortality rate
0-1	0.1-0.7%
2	1.9-2.1%
3	5.3-8.3%
4	12.7-19.3%
5	22.5-26.7%

Reference:

Wu BU, Johannes RS, Sun X, Tabak Y, Conwell DL, Banks PA. The early prediction of mortality in acute pancreatitis: a large population-based study. Gut. 2008;57(12):1698-1703. doi:10.1136/gut.2008.152702

Ranson's score	Mortality rate
0-2	~1%
3-5	15-20%
6	40%
>6	100% (associated with more systemic complications)

Reference:

Ranson JH, Rifkind KM, Roses DF, Fink SD, Eng K, Spencer FC. Prognostic signs and the role of operative management in acute pancreatitis. Surgery, gynecology & obstetrics. 1974;139(1):69–81.