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Time above MIC calculator for beta-lactams

mg
Hours
L/kg
kg
Hours
mg/L

Time above MIC (T > MIC)

%

 

Formula

Time above MIC calculator for beta-lactams

Where
ln = natural logorithm;
Vd = volume of distribution (L/kg);
BW = Body weight (kg);
T 1/2 = Serum half-life (hours); and
DI = dosing interval (hours)

 

Reference

Turnidge JD. The pharmacodynamics of β‐Lactams. Clinical Infectious Diseases. 1998;27(1):10-22. doi:10.1086/514622