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Table 7.2 Cost comparison of selected I.V. and P.O. antibiotics
| Antibiotics | Usual dosage | Cost (HK$/day) |
|---|---|---|
| Aminoglycosides | ||
| I.V. gentamicin1 (3.5 mg/kg/day) | 180 mg q24h | 11.2 |
| I.V. tobramycin1 (3.5 mg/kg/day) | 180 mg q24h | 230 |
| I.V. amikacin1 (15 mg/kg/day) | 750 mg q24h | 102 |
| Penicillins | ||
| I.V. ampicillin | 500 mg –1 g q6h | 9–18 |
| I.V. cloxacillin | 500 mg –1 g q6h | 17–33 |
| I.V. amoxillin-clavulanate | 1.2 g q8h | 24 |
| I.V. ampicillin-sulbactam | 1.5 g q6h | 66 |
| I.V. ticarcillin-clavulanate | 3.2 g q6h | 183 |
| I.V. piperacillin | 4 g q8h | 74 |
| I.V. piperacillin-tazobactam | 4.5 g q8h (4.5 g q6h) |
57 (76) |
| Cephalosporins | ||
| I.V. cefuroxime | 750 mg q8h | 9 |
| I.V. cefazolin | 1 g q8h | 8 |
| I.V. ceftriaxone | 1 g q12h | 10 |
| I.V. cefotaxime | 1 g q8h | 12 |
| I.V. cefoperazone-sulbactam (Sulperazon) | 1 g q12h | 11 |
| I.V. cefepime | 1 g q12h | 80 |
| I.V. ceftazidime | 1 g q8h | 36 |
| I.V. ceftaroline | 600 mg q12h | 688 |
| Carbapenems | ||
| I.V. meropenem | 500 mg q8h (1 g q8h) |
59 (98) |
| I.V. imipenem-cilastatin | 500 mg q6h | 129 |
| I.V. ertapenem | 1 g q24h | 230 |
| Fluoroquinolones | ||
| I.V. moxifloxacin | 400 mg q24h | 312 |
| P.O. moxifloxacin | 400 mg once daily | 34 |
| I.V. levofloxacin | 500 mg q24h | 58 |
| P.O. levofloxacin | 500 mg once daily | 1 |
| I.V. ciprofloxacin | 400 mg q12h | 1,354 |
| P.O. ciprofloxacin | 500 mg b.d. | 2 |
| Macrolides | ||
| I.V. clarithromycin | 500 mg q12h | 236 |
| I.V. azithromycin | 500 mg q24h | 109 |
| I.V. erythromycin | 500 mg q6h | 2,332 |
| Others | ||
| I.V. metronidazole | 500 mg q8h | 14 |
| I.V. vancomycin | 1 g q12h | 54 |
| I.V. linezolid (P.O. linezolid) | 600 mg q12h (600 mg b.d.) |
960 (910) |
Note: Approximate cost updated as of June 2016 in HA.
- 1Dosage for a typical 50 kg person.
